Research
The fields we study
Our Research
● Cancer Biology
There are many proposed causes and mechanisms to explain the formation and progression of various cancers. Although there have been extensive studies on the pathogenesis of human cancer, there are still limitations to overcoming cancer. Our laboratory is focusing on the researches of human breast cancer, one of the most commonly occurring cancers in women worldwide. Consequently, we are conducting epigenetic breast cancer research using multiple omics analysis, clinical data, patient-derived models, animal models, experimental methods, and bioinformatics.
● Epigenetics
Understanding how the genome becomes spatially organized and folded inside the nucleus is central to understanding how chromosomes function in normal development and in disease such as cancers. Our research allows us to integrate levels of chromatin compaction, chromosome intermingling, and the epigenetic state of large domains in a genome-wide manner.
● Comparative Oncology
Comparative oncology is the study of cancers in companion animals for the determination of their translational relevance to human cancers. Our laboratory develops key biomarkers to better understand the mechanisms of cancers through comparative genetic and epigenetic approaches to cancers in companion animals and humans and suggests solutions for diseases.